Figure 1

Synthesis strategy for NIPAAM/VP/PEG-A co-polymeric nanoparticles. Please refer to text for additional details. NIPAAM = N-isopropylacrylamide; VP = N-vinyl-2-pyrrolidone (VP); PEG-A = poly(ethyleneglycol)monoacrylate; MBA = N,N'-Methylene bis acrylamide (MBA), APS = ammonium persulphate (APS); FAS = Ferrous ammonium sulphate; TEMED = Tetramethylethylenediamine.