Fig. 1

Confocal laser scanning microscopy images of CAL-33 cells incubated for 28 h with free mTHPC (a, d), 50 nm M-Lipidots (b, e) and 120 nm M-Lipidots (c, f) in monolayers (a–c) and spheroids (d–f). Concentration for all treatments: 7.34 µM mTHPC. Scale bar 50 µm