Fig. 6
From: Advances in nanomedicines for lymphatic imaging and therapy
Copyright © 2022 The Authors
Design and partial characterization of gene-engineered cell membrane nanovesicles for integrated antigen self-presentation and immune checkpoint blockade. A Generation of DCNVs derived from adenovirus-infected mature dendritic cells. B Schematic illustration of the generation of DCNV-rAd-Ag. C Cryo-electron microscopy. D Dynamic light scattering analyses. E The western blot on membrane proteins from DCNV-rAd-GFP. F Comparison of upregulated immune-response-related proteins in NVs and DCs. G The relative abundance of antigen presentation and migration-related proteins on DCNV-rAd-GFP [100].