Fig. 4

In vivo specificity and bio-distribution of LP-S in mice bearing CAL27 cells. (a) NIR imaging of LP-S or ICG in mice with axillary subcutaneous tumor (red circle) at different time points after administration (4 h, 24 and 48 h). (b) Overlay of fluorescence images over white light images of LPS or ICG in mice with subcutaneous tumors on the back (red circle) at different time points after administration (4 h, 24 and 48 h), as well as the tissue bio-distribution after 48 h of administration