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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: A versatile engineered extracellular vesicle platform simultaneously targeting and eliminating senescent stromal cells and tumor cells to promote tumor regression

Fig. 6

Targeting ability of uPA-sEVs-siSrc in vivo. (A) Ex vivo fluorescent images of the main organs (heart, lung, liver, spleen, kidney) and tumor at 8 h post-injection. (B) Quantitative biodistribution of PKH26-labelled sEVs and uPA-sEVs-siSrc in the main organs and tumors. (C) Biodistribution of PKH26-labelled sEVs and uPA-sEVs-siSrc in tumor sections. Nuclei were stained with DAPI. Scale bar = 20 μm. (D) Quantitative biodistribution of PKH26-labelled sEVs and uPA-sEVs-siSrc in the tumor sections. **p<0.01; ***p<0.001; ****p<0.0001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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