Fig. 7
Anti-tumor effect of exoscFv/siLPCAT1 in vivo. (A) Schematic illumination of the experimental procedure. (B) Change of body weight of BALB/C nude mice treated with exoscFv/siLPCAT1, exoscFv/siNC or PBS, *p < 0.05, ns, not significance, n = 5 mice per group. Exosomes dosage = 5 mg/kg. (C) Representative bioluminescent images of BM tissues of nude mice treated with exoscFv/siLPCAT1, exoscFv/siNC or PBS at indicated time intervals after injection, n = 5 mice per group. (D) The signals of LPCAT1 (Green), ki67 (Green) and tunel (Green) in BMs sections were detected by confocal fluorescence imaging. Scale bar = 50 μm