Fig. 1
From: Engineered nanoparticles promote cardiac tropism of AAV vectors
ePL synthesis and characterization. a Schematic showing PLGA composition and degradation in vivo. b Schematic of ePL particle synthesis by nanoprecipitation. c Size distribution and zeta potential of ePL by DLS. d Transmission electron microscopy (TEM) examination of ePL shows that ePL particles are spherical in shape. e Biodistribution of ePL labeled with fluorescent europium cryptate 1 h after i.v. injection, showing significant accumulation in the liver (n = 3 animals per group)