Table 4 Patents enlisting the gene delivery with iron-based nanoparticles
From: Recent progress of iron-based nanomaterials in gene delivery and tumor gene therapy
Patent number | Publishing date | Nanoparticles | Integrated component | Reference |
|---|---|---|---|---|
US11305024 B2 | Apr 2022 | Iron oxide NPs | siRNA | [110] |
US20210154323 A1 | May 2021 | Iron oxide NPs | Peptide/protein | [111] |
US20200146995 A1 | May 2020 | Iron oxide NPs | Protein/nucleotides | [112] |
US10568970 B2 | Feb 2020 | USPIO | Nucleic acid | [113] |
US10286073 B2 | May 2019 | Magnetic NPs | CRISPR/Cas9 | [114] |
EP2396039 B1 | Aug 2018 | Superparamagnetic iron oxide NPs | pDNA with IL-12 gene | [115] |
US9675714 B1 | Jun 2017 | Superparamagnetic iron oxide NPs | DNA | [116] |
US9649388 B2 | May 2017 | Magnetic NPs | Double-stranded oligo RNA | [117] |
US9050362 B2 | Jun 2015 | PEI-PAAIO | pDNA | [118] |
KR101313180 B1 | Sep 2013 | Magnetic NPs | Nucleic acid | [119] |
KR20130045078 | May 2013 | Magnetic NPs | Gene | [120] |
US2012156686 A1 | Jun 2012 | MNP-SiO2 | DNA/antibodies | [121] |
KR20110105568 A | Sep 2011 | Iron oxide NPs | DNA/RNA | [122] |
US07846201 B2 | Dec 2010 | Magnetic NPs | Nucleic acid/pDNA | [123] |
US7459145 B2 | Dec 2008 | Magnetic NPs | Nucleic acid/peptide | [124] |
US20070059775 A1 | Mar, 2007 | Iron oxide NPs | Peptide | [125] |
WO2006055447 A2 | July 2006 | USPIO | Oligonucleotide | [126] |