Fig. 5
From: Combined SERS-Raman screening of HER2-overexpressing or silenced breast cancer cell lines
Raman spectra of the scrambled- and HER2-silenced SKBR3 cells (clone 3). (A): Median IQR spectra of scrambled (lime) and HER2-shRNA SKBR3 (red) with PCA loadings expressing high variance, as black lines (y is offset for clarity). Vertical dash lines are single peaks of interest; cyan vertical bands are relevant biological bands in cell classification. (B) The box plot of distribution of PCA scores for PC4 for the scrambled SKBR3 and silenced counterpart is shown, with a Wilcoxon statistic. (C) The score plot of PC1-PC4, evidencing the best spatial separation among scrambled and silenced SKBR3, is shown