Fig. 27
From: Recent advances in gene delivery nanoplatforms based on spherical nucleic acids
permission was received from ref [165]
(A) Schematic model depicting the effects of targeting MFG-E8 gene expression in macrophages on intestinal epithelial homeostasis. Inhibition of miR-99b stimulated the migration of intestinal epithelial cells in LPS-induced septic mice. (B) Images of the small intestine processed for BrdU/DAPI staining. (Note: green and blue colors show BrdU-labeled cells and nuclei, respectively). (C) Quantitative analysis discovered that SNA-NC anti-miR99b treatment increased enterocytes’ migration along the crypt-villus axis in LPS-induced septic mice. n = 3. **P.