Table 4 Calculation results of scleral permeation for Papp and Jss(n = 3, \(\overline{x}\)±s); *p<0.05
From: Preparation and in vivo and ex vivo studies of sirolimus nano-in-situ gel ophthalmic formulation
Biofilm | Formulation sample | Papp(cm/h) | Jss(µg/cm2/h) |
|---|---|---|---|
Sclera | SR-SUS | (0.704 ± 0.330)×10− 3 | 0.704 ± 0.330 |
SR-SUS-ISG | (1.929 ± 0.621)×10− 3* | 1.929 ± 0.621* |