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Fig 2 | Journal of Nanobiotechnology

Fig 2

From: Nebulized milk exosomes loaded with siTGF-β1 ameliorate pulmonary fibrosis by inhibiting EMT pathway and enhancing collagen permeability

Fig 2

M-Exos can escape lysosomes and collagen penetration. (A) Colocalization images of M-Exos and lysosomes in BEAS-2B cells. Red, green, and blue fluorescence represent fluorescence of MExo, lysosome, nucleus after staining. The bar is 25 μm. (B and C) Protein expression of α-SMA and col I in BLM-treated HFL1 cells. (D) The ability of M-Exos to penetrate the collagen barrier in HFL1 cells. Blue fluorescence indicates DAPI-labeled nuclei. M-Exo-DiR indicates that M-Exos labeled with DiR were visible under red light. FAM siRNA indicates that FAM-labeled siRNA shows green light, and Merge indicates the overlap of two fluorescent signals at the same position in the cell

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Journal of Nanobiotechnology

ISSN: 1477-3155

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