Fig. 1
From: A bioinspired supramolecular nanoprodrug for precision therapy of B-cell non-Hodgkin’s lymphoma
The novel ROS responsive linker-based dimeric fludarabine prodrug (F2A) and thymidine derivatives-modified polysialic acid (TPSA) exhibit an interaction similar to “Watson–Crick base pairing” in aqueous solution. The supramolecular nanoprodrug (F@TPSA) is formed by hydrogen bond and hydrophobic interaction