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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Circulating extracellular vesicle-derived miR-1299 disrupts hepatic glucose homeostasis by targeting the STAT3/FAM3A axis in gestational diabetes mellitus

Fig. 1

EVs isolated from the plasma of pregnant women and internalization of EVs by liver cells. (A) Representative transmission electron microscopy images of isolated EVs. EVs displayed a cup-shaped morphology. (B) The distribution of EVs size by NTA analysis. (C) The expressions of EVs markers (CD81, CD63, and TSG101), and cellular markers (Calnexin) were assessed by western blotting. Appearance of PKH67-stained EVs in THLE-2 cells (D), and liver of recipient mice (E) after 24 h administration of EVs. DAPI stained the nucleus blue, and PKH67 stained EVs green (bar, 50 μm)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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