Skip to main content
Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: A nanoscale visual exploration of the pathogenic effects of bacterial extracellular vesicles on host cells

Fig. 1

Mitochondria fission effect of S. aureus EV-mediated infection. (A) Representative STORM images of mitochondria in epithelial keratinocyte (HaCaT) cells treated with S. aureus EVs (left) or S. epidermidis EVs (right) after 30 min of EV infection. Enlargement of the boxed region is shown at the bottom. Schematic diagrams are shown together. (B) Quantitative analysis of the mitochondrial ultrastructural changes in terms of the ratio of long (with > 5 μm longest diameter) and short mitochondria (with < 5 μm longest diameter) and ratio of branched mitochondria from STORM images. (n = 10, mean ± SD) (C) Representative TEM images of HaCaT cells treated with S. aureus (left) or S. epidermidis (right) EVs after 30 min of EV infection. Arrows: mitochondrial fission. (D) Quantitative analysis of the size of the mitochondria in terms of the longer diameter from TEM images. (n = 10, mean ± SD) (ns: p > 0.05, ***p < 0.001) Scale bars: (A) 5 μm (top), 1 μm (bottom). (C) 1 μm

Back to article page

Journal of Nanobiotechnology

ISSN: 1477-3155

Contact us