Fig. 4

A) The inhibitory effects of different formulations on the proliferation of 4T1 cells, determined by MTT assay. B) The ability of 4T1 cells treated with different formulations to produce CRT was determined by flow cytometry. C) ELISA assay of extracellular HMGB-1 release from 4T1 cells incubated with different formulations. D) Extracellular secretion of ATP. E) Confocal images of CRT and HMGB1 expression on the surface of 4T1 cells. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)