Scheme 1

A) Fabrication of the transformable self-delivered supramolecular nanomaterial NLG919@CF though host–guest complexation between Ce6-CD and Fc-pep-PEG. B) Schematic illustration of local immune microenvironment changes in tumors before and after treatment. C) Schematic illustration of the mechanism of NLG919@CF combined with an anti-PD-1 antibody in the coordinated treatment of tumors