Fig. 4

Enhanced promotion of antitumor lymphocyte activation in irradiated tumors by NBTXR3 + PRT + αPD1 Treatment. A UMAP color-coded for lymphocyte activation markers. B The expression level of antitumor lymphocyte activation markers in cytotoxic lymphocytes. The expression levels of activation markers were assessed using the Kruskal–Wallis test. A p-value of < 0.05 was considered to indicate statistical significance. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. NS, not significant