Fig. 3

Nano-drugs improve hypoxic microenvironment at tumor site. (A) Schematic illustration of FeS₂/CoS₂@PEG NSs for efficient PTT/PDT/CDT. (B) Photographs of mice and H&E staining of tumors after two weeks treatments (Adapted with permission from reference [56]) (C) Schematic illustration of the synthesis route of BSA-MHI148@SRF nanoparticles and the mechanism illustration of enhancing tumor photodynamic immunotherapy by re-oxygenation and immune re-sensitization strategy mediated. (D) Representative fluorescence images of VEGF-A expression in tumor tissues (Adapted with permission from reference [68])