Fig. 1

Apelin-13 is downregulated in spinal cord injury (SCI) rats SCI models were established as described. (A) After 28 days of modeling, spinal cord tissues were collected from model rats sacrificed under anesthesia and examined for histopathological characteristics using H&E staining. (B-C) The Basso-Beattie-Bresnahan (BBB) Locomotor Rating Scale and inclined-plane test were used to evaluate the behavioral outcomes and motor ability of rats from different groups. (D) The protein levels of Apelin-13 in spinal cord tissues were determined using Immunoblotting. n = 6 or 3, ** p < 0.01