Fig. 4

Biodistribution of LPs in BALB/c nude mice. (A) Real-time fluorescence imaging of control, free Cy5.5, Cy5.5-LPs, and Lf-Cy5.5-LPs groups at various time points post-injection. (B) Accumulation of Cy5.5 fluorescent probe in the brain and other organs at 4 and 24 h after injection. (C) Quantification of fluorescence intensity in the brain and other organs at 4 h after injection. Data are presented as the mean ± SD (n = 5). *p < 0.05, **p < 0.01, ***p < 0.001