Fig. 8

Therapeutic mechanisms of the NM-PB nanozymes in mice UC model. A-C) KEGG pathways enrichment analysis of DEGs in the DSS group Vs. the PBS group, PB group Vs. the DSS group, and the NM-PB group Vs. the DSS group. D-G) The expression of mRNAs for Csf3, Cxcl2, Cxcl3, and Il20ra as determined by RT-qPCR in the colon tissues after different treatments. H) Validation of the expression of Csf3, Cxcl2, Cxcl3, and Il20ra in colon tissues after different treatments, measured by RT-qPCR and Western blot. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. one-way ANOVA, Tukey’s multiple comparison test