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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Decellularized tissue matrices hydrogels functionalized with extracellular vesicles promote macrophage reprogramming and neural stem cell differentiation for spinal cord injury repair

Fig. 8

Key Factors Regulating Reprogramming of M1 Macrophages by DSCM@EVs. Note: (A) Path diagram of LASSO coefficient for differentially expressed genes in RNA-seq; (B) Cross-validation curve for differentially expressed genes in RNA-seq; (C) Venn diagram showing intersection of LASSO genes, GEO merged data, differentially expressed genes, core genes of M1-M2 macrophages, and differentially expressed genes in RNA-seq; (D) Bar chart of Slamf9 expression in RNA-seq, where the con group represents M1 macrophages and the treat group represents M1 macrophages treated with DSCM@EVs; (E) Bar chart of Slamf9 expression in GEO merged dataset; (F) Analysis of correlation between Slamf9 in GEO merged dataset and infiltration of M1 macrophages

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Journal of Nanobiotechnology

ISSN: 1477-3155

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