Fig. 7

CZP mediated therapy on 4T1 tumor. (a) Schematic illustration of the experimental schedule for 4T1 tumor-bearing mice. (b) Temperature-time curves and (c) thermal images of tumor-bearing mice under NIR irradiation (1 W/cm², n = 5). (d) Body weight changes of mice over 12 days. (e) Tumor growth curves, (f) tumor weights and (g) corresponding photographs of primary and distant tumors (n = 5). Representative flow cytometry plots and corresponding quantifications of (h, i) mature DCs in TDLNs, (j, k) CD3⁺ CD8⁺ T cells, (l, m) Tregs, and (n, o) M2 phenotype tumor-associated macrophages in tumors from mice following various treatments (n = 4). (p) Immunofluorescence staining of CD8⁺ and CD4⁺ T cells, TUNEL, and H&E staining of tumor tissues from mice given various treatments