Fig. 4
From: Remodeling tumor microenvironment using prodrug nMOFs for synergistic cancer therapy
a Schematic illustration of the therapeutic intervention in the H22 subcutaneous tumor-bearing mouse model. b Respective tumor growth curves for each tumor-bearing mouse in different groups. c The average tumor growth patterns exhibited by H22 tumor-bearing mice following different treatments. d The weight of extracted H22 tumors after different treatments. e The photographs of extracted H22 tumors. f The changes in body weight of H22-tumor-bearing mice in different treatment groups. g Analysis of AMPK enzyme activity in H22 tumor tissue from different treatment groups (n = 5). h H&E staining, TUNEL labeling, and Ki-67 staining of tumors in mice subjected to various treatments for 18 days. All Error bars represent mean ± S.D. n = 5 biologically independent samples. (*p < 0.05, **p < 0.01, ***p < 0.001)