Nanophotonic-enhanced photoacoustic imaging for brain tumor detection

Table 2 Summary of important nanoparticles contrast agents used for photoacoustic brain imaging

Nanoparticle type	Components	Properties	Laser wavelength	Application	Refs.
PDI NPs	PDI/DSPE-mPEG-5000	Enhanced PA signals, water stability	700 nm	Deep brain tumor imaging	[194]
ICG-coated Iron oxide NPs	ICG-SPIO	Strong PA signal FDA-approved	Not specified	Brain tumor imaging	[187]
MoS₂-ICG hybrid NPs	MoS₂-ICG (nanosheets)	Enhanced NIR absorption	Not specified	Brain tumor imaging	[188]
DOX-HCu NPS	Copper based NPs, DOX	Biodegradability high efficacy	Not specified	Imaging FUS-mediated BBB opening	[189]
A1094 NPs	Organic mesionic dye Arg-Gly-Asp-modified hepatitis B virus core Proteins	Aggregation-induced absorption enhancement	1000–1700 nm	Deep brain tumor imaging	[22]
PDI NPs	PDI	Efficacy through EPR effect Low toxicity	700 nm	Deep brain tumor imaging	[14]
PLGA-PEG NPs	Benzobisthiadiazole, PLGA-PEG	Biodegradable Strong PA signals	Not specified	Brain vascular visualization	[14]

PDI, perylene-3,4,9,10-tetracarboxylic diimide; ICG, indocyanine green; MoS₂, molybdenum disulfide; PLGA, poly (lactic-co-glycolic acid); PEG, polyethylene glycol; DOX, doxorubicin

ISSN: 1477-3155