Fig. 2
BRAF mutation is a poor prognostic factor in CRC patients. (A) K-M survival curves of patients with BRAF mutation and wild-type CRC. (B) Multivariate COX regression model analysis of gender, stage and BRAF mutation status in CRC patients. (C) K-M survival curve of BRAF expression level in BRAFMT CRC. (D) Representative IHC images of BRAFV600E and KI-67 in CRC tissues. The scale bar represents 10 μm for the 10x objective and 5 μm for the 20x objective. (E) KI67 positivity rate in CRC tissues with BRAFV600E or BRAFWT. The data are reported as the means ± SDs of the experiments (n = 3). Two-tailed Student’s t-tests, **p < 0.01