Fig. 3
Effects of NP-NAR supplementation on hepatic transcriptome. (A) Venn diagram. (B-C) volcanic plot of DEGs in different groups. (B) NAR vs. MC groups. (C) NP-NAR vs. MC groups. DEGs were screened on p-value < 0.05 and | log2 (Fold Change)| > 1. (D-E) GO enrichment analysis in different groups. (D) NAR vs. MC groups. (E) NP-NAR vs. MC groups. (F-G) KEGG enrichment analysis in different groups. (F) NAR vs. MC groups. (G) NP-NAR vs. MC groups. (H) heat map analysis of lipid metabolism related genes across the groups. (I) GSEA enrichment analysis. (J) the PPI network with 20 hub genes in different groups. (K) heat map analysis of top 10 hug genes. (#) p < 0.05, (##) p < 0.01, and (###) p < 0.001 compared to the NC group. (∗) p < 0.05, (∗∗) p < 0.01, and (∗∗∗) p < 0.001 compared to the MC group