Fig. 6

NP-NAR alleviates the structure of gut microbiota. (A) PCoA score plot based on weights. (B) NMDS score plot based on Bray − Curtis. (C) Shannon index. (D) Simpson index. (E) the F/B ratio. Relative abundances of intestinal microbes at the phylum level (F) and genus level (G). (H) Heatmap analysis of top 35 genus. Relative abundance of significantly different gut microbiota at the genus level between NC and MC groups (I) and NP-NAR and MC groups (J). Each value was expressed as the mean ± SD (n = 6). (#) p < 0.05, (##) p < 0.01, and (###) p < 0.001 compared to the NC group. (∗) p < 0.05, (∗∗) p < 0.01, and (∗∗∗) p < 0.001 in relation to the MC group. (Δ) p < 0.05, (ΔΔ) p < 0.01, and (ΔΔΔ) p < 0.001