Fig. 8
From: Multidimensional applications of prussian blue-based nanoparticles in cancer immunotherapy
(A) Schematic illustration of the preparation process and behavior of HMPB/BLZ945/anti-SIRPα@ATRA@fibrin for cancer immunotherapy in vivo. The immunotherapeutic gel at the surgical site released ATRA and HMPB/BLZ945/anti-SIRPα to induce CSC differentiation and TAMs reprogramming. Reproduced with permission [193]. Copyright 2023, Elsevier Ltd. (B) Schematic illustration of the synthetic of LMWHA-MPB nanoparticles and HMME-loading LMWHA-MPB nanoparticles inhibits the proliferation and metastasis of 4T1 tumor in vivo [194]. Copyright 2019, Europe PMC. (C) Schematic illustration of the preparation of G/APH-M and G/APH-M-based radiotherapy in combination with anti-PD-L1 to enhance glioblastoma radio-immunotherapy [195]. Copyright 2023, Wiley-VCH GmbH. (D) Schematic illustration of lactate consumption combined with siPD-L1 to synergistically improve tumor immunotherapy [199]. Copyright 2023, Elsevier Ltd. (E) Schematic illustration of the multifunctional nanoplatform (SP94-PB-SF-Cy5.5 NPs) for HCC-targeted multimodality imaging and combined PTT/SF treatment. Reproduced with permission [200]. Copyright 2019, American Chemical Society