Scheme 1
From: Multidimensional applications of prussian blue-based nanoparticles in cancer immunotherapy
Multidimensional application of Prussian blue-based nanoparticles in cancer immunotherapy. ICD, immunogenic cell death; TAA, tumor-associated antigen; CRT, calreticulin; HMGB1, high-mobility group protein box 1; ATP, adenosine triphosphate; iDCs, immature DCs; mDCs, mature DCs; PD1, programmed death receptor 1; PDL1, programmed death receptor ligand1; MHC, major histocompatibility complex; TCR, T cell receptor; TME, tumor micro-environment; TAMs: tumor-associated macrophage M2-TAMs, M2 type tumor-associated macrophages; M1-TAMs, M1 type tumor-associated macrophages; MDSC, myeloid-derived suppressor cells; Treg cell, regulatory T cells; Th cell, helper T cell; CTL, cytotoxic T lymphocyte; m6A, N6-methyladenosine; mRNA, messenger RNA; FPN, ferroportin