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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: A novel perspective on the regulation of cardiac cell beating: cardiac cell under mechanical stimulation acts as “cell activation button” to activate adjacent cardiac cell

Fig. 4

Calcium imaging reveals the bioelectrical signal conduction mechanism. (a-b) Spontaneous calcium transients in unstimulated cells, showing hierarchical signaling from a “dominant cell” to adjacent cells. (c-d) Mechanical stimulation induces calcium influx in the activation cell, which propagates to the target cell via intercellular junctions. Scale bar: 30-µm

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Journal of Nanobiotechnology

ISSN: 1477-3155

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