Fig. 7

In vivo AuNC-enhanced radiotherapy in a subcutaneous KB tumor mouse model. (a) Schematic of the experimental timelines. (b) Irradiation setup and X-ray CT scan showing the tumor (arrow). Time-course post irradiation (means ± 1 s.d.: n = 5 per group) of (c) tumor volume normalised to the pre-treatment value, (d) normalised body weight and (e) survival profile for each treatment group. (f) Treatment information for each group and response analysis are summarized in the table. For survival statistical analysis, the log-rank (Mantel-Cox) test was used to compare survival differences across 4 groups. To account for multiple comparisons across 4 pairs, the significance threshold was adjusted using the Bonferroni correction. ‘ns’ indicates no statistical significance, while ‘**’ denotes a p-value < 0.01