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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Mitochondria-targeted nanovesicles for ursodeoxycholic acid delivery to combat neurodegeneration by ameliorating mitochondrial dysfunction

Fig. 6

Transcriptome sequencing of the striatum in PD mice was treated with UDCA-NVs-TPP. a) volcano plot of DEGs between the PD and UDCA-NVs-TPP group. b) Heatmap analysis was conducted to compare DEGs between the PD and UDCA-NVs-TPP group. c) Bubble plot of the top 20 enriched WikiPathways for upregulated DEGs between the PD and UDCA-NVs-TPP group. d) Chord diagram of the top 10 enriched WikiPathways for overall DEGs between the PD and UDCA-NVs-TPP group. e) Protein–protein interaction (PPI) networks associated with key signaling pathways. f) Bubble plot of the top 20 enriched KEGG pathways for downregulated DEGs between the PD and UDCA-NVs-TPP group

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Journal of Nanobiotechnology

ISSN: 1477-3155

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