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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Renal-clearable and tumor-retained nanodots overcoming metabolic reprogramming to boost mitochondrial-targeted photodynamic therapy in triple-negative breast cancer

Fig. 2

Optical properties, and drug release of MSPC in the response of pH and NIR irradiation. (A) Acidic pH-responsive drug release profiles of MSPC. (B, C) Absorbance spectra and fluorescence spectra of MSPC in PBS at (B) pH 7.4 and (C) pH 6.0. (D, E) The fluorescence spectra of MSPC in PBS at (D) pH 7.4 and (E) pH 6.0. (F, G) absorbance spectra of DPBF incubated with MSPC in PBS at pH 7.4 and 6.0 after light irradiation. (H) The percentage of CO released from MSPC by different irradiation time. (I) Schematic illustration: MSPC for fluorescence imaging, pH/ROS cascade responsive chemotherapy, and PDT with prolonged tumor retention in TME. Data presents as mean ± SD, n = 3 (*p < 0.05, **p < 0.01, ***p < 0.001)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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