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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Harnessing the power of traceable system C-GAP: homologous-targeting to fire up T-cell immune responses with low-dose irradiation

Fig. 9

scRNA-seq Analysis of the Impact of C-GAP on Gene Expression in CD8+ Cells. A, B Expression of immune-related genes in CD8+ T cell subclusters of the Treatment group. C UMAP Plot of different CD8+ T cell subpopulations from Treatment group with lines represent cell density. D UMAP plot of the expression and distribution of TNF-α in CD8+ T cell subpopulations from Treatment group. E UMAP plot of the expression and distribution of CCL5 in CD8+ T cell subpopulations from Treatment group. F-G Representative Images and Semi-Quantitative Analysis of TNF-α and CCL5 Expression in Mice Tumor Tissue from Different Groups Detected by Immunofluorescence Staining (n = 4). H–L Differential Gene Expression Analysis of Five CD8+ T Cell Subclusters within the Treatment Group

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Journal of Nanobiotechnology

ISSN: 1477-3155

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