Fig. 2
Ferroptosis in liver fibrotic tissues is inhibited by MSCs. (A) Venn diagram identifying DEGs associated with MSC treatment. (B) Heatmap of RNA sequencing results from Control, CCl4, and CCl4 + MSC groups. (C) GO analysis of DEGs modulated by MSCs. (D) KEGG analysis of DEGs modulated by MSCs. (E) Western blot of Cox2 and Sod1 expression in liver tissues. (F) Serum iron levels measurement. (G) SOD levels measurement in liver tissues. (H) MDA levels measurement in liver tissues. (I) Immunofluorescence staining of BODIPY in liver tissue. Scale bar = 20 μm. The data are presented as the mean ± SEM from at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 indicate significant differences between the indicated groups