Fig. 5
From: Pharmacokinetics modulation in solid tumors through thrombin-embedded nanomedicine
In vitro biological performance of a variety of prodrug nanomedicine. (a) Real time CLSM measurement for tracing intracellular trafficking of SN38; (b) Detailed analysis in pertinent of the intracellular distribution of SN38 and endolysosomes at 2Â h; (c) Time dependent measurement for quantification of the intercellular fluorescence intensities of SN38; (d) Cytotoxic potencies of a variety of SN38 therapeutics against a panel of cancerous cells