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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Selenium nanoparticles activate selenoproteins to mitigate septic lung injury through miR-20b-mediated RORγt/STAT3/Th17 axis inhibition and enhanced mitochondrial transfer in BMSCs

Fig. 4

SeNPs@CS synergizes with BMSCs to promote mitochondrial repair in damaged AECII cells. (A, B) Qualitative and quantitative detection of mitochondrial membrane potential. (C) Detection of mitochondrial ATP content. (D, E) Qualitative and quantitative detection of mitochondrial calcium ion content. (F) Detection of mitochondrial OCR content. (G, H) Qualitative and quantitative detection of cell apoptosis by flow cytometry. (I) Detection of mitochondrial NAD+ content. (J) Transmission electron microscopy (TEM) examination of mitochondrial structure. G1: LPS; G2: BMSCs; G3: OE-miR-20b-BMSCs; G4:SeNPs@CS + OE-miR-20b-BMSCs. ***(P < 0.001), **(P < 0.01), *(P < 0.05)

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