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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Influence of salt solution on the physicochemical properties and in vitro/ in vivo expression of mRNA/LNP

Fig. 2

The effect of dilutions on mRNA/LNP. (A) Schematic of the LNP preparation method with different dilutions. (B) Transfection efficiency of mRNA/LNP in DC2.4 and AML12 cells. (C) Correlation between physicochemical properties, transfection ability in vitro and dilutions of mRNA/LNP. (D) Correlation of dilution salt concentration and zeta potential. (E) The effect of dilution pH on PDI. The relationship of particle size and LNPs transfection in DC2.4 (F) and AML12 (G) cells. Data was presented as mean ± SD. *p < 0.05

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Journal of Nanobiotechnology

ISSN: 1477-3155

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