Fig. 7

PGLNs influenced the metabolic disorder of LPS-induced RAW264.7 cells. (A) Illustration of metabolomics analysis. (B) Quantity and classification of metabolites. (C) PCA score plots for various groups (Con, LPS and LPS + PGLNs). (D) PCA score plots for Con vs. LPS and LPS vs. LPS + PGLNs. (E) OPLS-DA score plots for Con vs. LPS and LPS vs. LPS + PGLNs. (F) OPLS-DA permutation test for Con vs. LPS and LPS vs. LPS + PGLNs. (G) Heatmap of hierarchical cluster analysis of metabolite changes (“red” and “blue” represent increased and decreased metabolite contents, respectively)