Fig. 4

Effects of the 32 miRNAs on dermal fibroblast proliferation, LPS-induced inflammatory responses, and TGF-β1-driven fibrosis. (A) Results of the CCK-8 assay. (B) NO synthesis of macrophages. (C) Results of the gel contraction assay. All statistical analyses were performed by one-way ANOVA with Tukey’s multiple comparison test. For (A), significance was compared with the control group; for (B) and (C), significance was compared with the NC group. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns, not significant. Data are presented as mean ± S.D