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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Oral administration of Momordica charantia-derived extracellular vesicles alleviates ulcerative colitis through comprehensive renovation of the intestinal microenvironment

Fig. 6

Biocompatibility evaluation of MCEVs. Cell viability was evaluated using the MTT assay after co-incubation with MCEVs for 12 h and 24 h in (A) RAW264.7 and (B) FHC cells. (C) Body weight change of mice that were gavaged with PBS and MCEVs for 7 days and were killed on day 9. Mice were gavaged with equivalent PBS as control. (D) Apoptosis analysis of cells after co-incubated with MCEVs for 24 h by flow cytometry. (E) Histological analysis of vital organs isolated from the mice on day 9 by H&E staining. (F) The blood routine assays. (G) The biochemical assays. Data were shown as mean ± SD. n ≥ 3, *: P < 0.05, **: P < 0.01, ***: P < 0.001, ns: P > 0.05, indicating no significance

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Journal of Nanobiotechnology

ISSN: 1477-3155

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