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Table 1 Comparison of Different Bone Cements'Properties and Applications

From: Biomaterial-based strategies for bone cement: modulating the bone microenvironment and promoting regeneration

Type

Mechanical Strength

Degradation Rate

Biocompatibility

Osteogenic Properties

Features

Refs.

PMMA

High(70–100 MPa)

Non-degradable

Moderate possible thermal necrosis during polymerization

Limited

High mechanical strength and stability

Modifiable for improved performance

Non-biodegradable

Limited bioactivity without modifications

[21,22,23,24,25]

CPC

Moderate (5–40 MPa)

18–36 months

Excellent similar to natural bone composition

Excellent osteoconductivity; natural bone bonding

Poor load-bearing strength

Good biocompatibility and osteoconduction

Relatively slow degradation rate

Limited osteogenic potential

[26,27,28,29,30]

MPC

Moderate (2–45 MPa)

7–10 months

Excellent due to Mg2+ being natural bone component

Good

through stimulating osteoblast differentiation

High early-stage strength

Fast-setting

Moderate degradation rate

Relatively low bioactivity

[31,32,33,34,35]