Fig. 10

Verification of the enhancement of osteogenic performance of scaffolds through mild NIR laser irradiation in vivo. (A) Process diagram for using shape-memory scaffolds to repair craniofacial bone injuries. (B–E) Representative 3D reconstruction images and analysis of the BMD, Tb.Th, and BV/TV of the newly formed bone in the defect areas following scaffold implantation and mild NIR laser irradiation for 12 weeks. (F–G) Staining of newly formed bone in the cranial defect area using H&E and Masson’s trichrome staining methods following 12 weeks of shape-memory scaffold implantation and mild NIR laser irradiation (n = 5)