Fig. 6

Unique optimization design of nanomaterial-loaded MN platforms for hair regrowth. (A) Blank MNs can improve perifollicular neovascularization [82]. Copyright 2022, Elsevier. (B) MN-assisted overcoming of the SC barrier, HF-targeting and penetration of lipid NPs [83]. Copyright 2020, Elsevier. (C) MNs with the switchable temperature-responsive ring can prolong MXD NPs action and be easily removed [84]. Copyright 2024, Elsevier. (D) DMN delivers PtNZs to treat AGA by scavenging ROS and promoting HFSC differentiation (a) [87]. Copyright 2024, Wiley-VCH. MN-aided PDA NPs function as low-dose ROS donors to realize controlled and efficient ROS intracellular delivery (b) [88]. Copyright 2024, Wiley‐VCH. (E) MN/LPN/miR-218 promote regeneration by regulating HF cycle [90]. Copyright 2022, Royal Society of Chemistry