Fig. 8

Therapeutic effect of HA-RM-Cel-BR on RA in vivo. (a) Establishment and treatment protocol of RA rat model. (b) Degree of toe swelling in different treatment groups. (c, f) Temperatures of inflamed paws measured by thermal imaging. (d) Arthritis function score in different treatment groups. (e) Photographs of inflamed joints in different treatment groups. (g) Micro-computed tomography (micro-CT) analysis of bone tissues in different treatment groups. Data are presented as mean ± SD (n = 6). *P < 0.05, **P < 0.01, and ***P < 0.001