Skip to main content
Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Ultrasmall platinum single-atom enzyme alleviates oxidative stress and macrophage polarization induced by acute kidney ischemia–reperfusion injury through inhibition of cell death storm

Fig. 7

Pt/SAE ameliorates I/R-Induced Nephrotoxicity by suppressing ferroptosis and PANoptosis. A Immunofluorescence staining of 4-HNE (red), Megalin (green) and DAPI (blue) in kidneys after I/R with Pt/SAE. Scale bar = 50 μm. B Representative immunoblots of ferroptosis-related proteins in kidney tissues. n = 3. C Immunofluorescence staining of GPX4 (red), Megalin (green) and DAPI (blue) in kidneys after I/R with Pt/SAE. Scale bar = 50 μm. D–F Representative immunoblots of PANoptosis-related proteins in kidney tissues. n = 3. G Immunofluorescence staining of ZBP1 (red), Z-DNA (green) and DAPI (blue) in kidneys after I/R with Pt/SAE. Scale bar = 50 μm. p-values are calculated using the Student’s two-tailed t-test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

Back to article page

Journal of Nanobiotechnology

ISSN: 1477-3155

Contact us