Fig. 2

Preparation and characterization of BT-apoEVs. (A) Schematic illustration of the preparation of BT-apoEVs. (B) FTIR analysis of apoEVs and BT-apoEVs. (C) XPS survey spectra of apoEVs and BT-apoEVs. (D) ApoEVs and BT-apoEVs observed by a confocal microscopy (Scale bar = 20 μm). (E) Representative TEM images of apoEVs and BT-apoEVs. (Scale bar = 200 nm). (F) Size distribution of apoEVs and BT-apoEVs measured by dynamic light scattering (n = 3). (G) Zeta potential of apoEVs and BT-apoEVs determined by dynamic light scattering (n = 3). (H) Binding affinity of apoEVs and BT-apoEVs with HAp (n = 3). **p < 0.01