The biological activity and potential of probiotics-derived extracellular vesicles as postbiotics in modulating microbiota-host communication

Table 2 Application of PEVs based on immunological activity and carrier properties

Bacterial producer	Support material	Activity and Usage	Reference
Lactobacillus druckerii*	TA-Mg	Improve wound microenvironment and promote wound tissue healing	[164]
Lactiplantibacillus plantarum *	Fucoxanthin	Improves gut microbiota and reduces colitis response	[165]
Lactiplantibacillus plantarum *	Fucoxanthin	Reducing hepatic lipid accumulation and disorders of lipid metabolism	[166]
E. coli Nissle 1917 serotype O6:K5:H1	SOST siRNA	Induce osteogenic differentiation of BMSCs and ameliorate OP	[175]
Saccharomyces boulardii CNCM I-745	Adriamycin	Adriamycin is internalised and absorbed by intestinal epithelial cells and transported to selected cells and tissues in the host	[167]
Lactobacillus animalis*	Cu-TCPP (tetrakis(4-carboxyphenyl) porphyrin) nanosheets	Enhances antimicrobial activity and enhances implant osteogenicity	[163]
Lacticaseibacillus casei DSM20011 & Lactiplantibacillus plantarum NCIBM 8826	Hydrogel	Improves wound healing and reduces scar formation	[162]

Abbreviations: BMSCs, Bone marrow mesenchymal stem cells; OP, Osteoporosis; Cu-TCPP, Tetrakis(4-carboxyphenyl) porphyrin; * Bacterial strain was not reported

ISSN: 1477-3155